A Call to Action to Control Hypertension: What will it take to improve health outcomes in medically underserved communities? The research seeks to gain an understanding of the gaps and barriers in medically underserved communities and the effect of their … Read More

Cardiac Fibroblast Phenotypes: Investigation of the Role of Mitochondrial Structure and Function More than 6 million Americans suffer from heart failure secondary to acute and chronic disease states that induce cardiac fibrosis. Fibrosis is the deposition of extracellular matrix that … Read More

Dynamic nitrosation - palmitoylation of endothelial CD36 regulates serum lipids My talk will focus specifically on a new post-translational modification of a fatty acid translocase CD36 and how this regulates lipid uptake into endothelium.  PhD Candidate Physiology, Isakson Lab, University of … Read More

Cell Signaling And Immune Cell Involvement In Neointima Formation Connexin (Cx) proteins form gap junctions, allowing for communication between cells. Alterations in gap junctions have been associated with pathological proliferation in disease since their discovery in the 1950s. Our studies … Read More

Toward a Therapy for Atherosclerosis - Discuss growth and composition of the arterial plaque, with possible targets of therapy - Discuss feasibility and drivers of atherosclerosis regression VP/Chair, Scientific Council, Global Clinical Development, Regeneron

Novel transgenic/chemogenetic models of oxidative stress in the cardiovascular system Dr. Michel’s seminar will discuss the development and application of chemogenetic approaches to dynamically modulate tissue-specific oxidative stress.  These studies have yielded new models of heart failure, neurodegeneration, and aortic … Read More

Extracellular vesicle-mediated communication in cardiovascular disease Extracellular vesicles (EVs) are produced by cells in the cardiovascular system, and they can be taken up by recipient cells to alter function. The contents and functions of EVs change during disease, and they … Read More